Health & body · 1986
Can liver tumors be associated with positive pregnancy tests even when pelvic organs appear normal?
Yes. In this report, two women with large liver tumors had positive pregnancy tests and markedly elevated blood hCG levels, even though their pelvic organs were found to be normal.
Details
This descriptive report presents two clinical cases: women aged 29 and 27 who had evidence of recent hemorrhage and large tumors of the liver. One tumor was successfully resected; the other patient died of blood loss.
The two lesions were almost identical and were indistinguishable from choriocarcinoma. Both patients had markedly elevated serum human chorionic gonadotropin (hCG) levels and positive pregnancy tests. Examination of the endometrium showed only proliferative endometrium, and the pelvic organs were found to be normal.
Immunoperoxidase stains of the liver tumors were strongly positive for hCG and human placental lactogen. Alpha-1-antitrypsin and alpha-fetoprotein tests were weakly positive, and one patient tested positive for carcinoembryonic antigen.
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